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Kiyotoshi Sekiguchi Selected Research

Syndactyly (Polysyndactyly)

5/2012Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.
4/2010Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes.
8/2006Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.

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Kiyotoshi Sekiguchi Research Topics

Disease

18Neoplasms (Cancer)
01/2018 - 01/2003
5Carcinoma (Carcinomatosis)
05/2011 - 01/2003
4Fraser Syndrome
05/2012 - 08/2006
4Glioma (Gliomas)
10/2005 - 10/2003
3Parkinson Disease (Parkinson's Disease)
01/2022 - 03/2014
3Syndactyly (Polysyndactyly)
05/2012 - 08/2006
3Breast Neoplasms (Breast Cancer)
11/2011 - 01/2005
3Experimental Sarcoma
04/2004 - 03/2003
2Myocardial Infarction
01/2020 - 01/2019
2Bullous Pemphigoid (Pemphigoid)
02/2015 - 02/2009
2Glioblastoma (Glioblastoma Multiforme)
01/2005 - 08/2004
1Nephrotic Syndrome (Syndrome, Nephrotic)
12/2021
1Infarction (Infarctions)
11/2021
1Thoracic Aortic Aneurysm
01/2021
1Hypoxia (Hypoxemia)
01/2020
1Cardiomyopathies (Cardiomyopathy)
01/2020
1Neurofibroma
11/2019
1Wounds and Injuries (Trauma)
01/2018
1Autoimmune Pancreatitis
01/2018
1Immunoglobulin G4-Related Disease
01/2018
1Liver Cirrhosis (Hepatic Cirrhosis)
12/2017
1Teratoma (Teratoid Tumor)
12/2017
1Stroke (Strokes)
02/2017
1Respiratory Hypersensitivity
01/2017
1Liver Diseases (Liver Disease)
01/2016
1Fibrosis (Cirrhosis)
01/2015
1Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature
05/2013
1Chronic Hepatitis (Chronic Active Hepatitis)
01/2013
1Bilateral Frontoparietal Polymicrogyria
01/2013
1Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa)
05/2012
1Marfan Syndrome (Marfan's Syndrome)
11/2011
1Lens Subluxation
11/2011
1Fibrosarcoma
11/2011
1Emphysema
11/2011
1Periodontal Diseases (Periodontal Disease)
11/2011
1Blister (Bulla)
04/2010
1Pulmonary Edema
03/2010
1Idiopathic Pulmonary Fibrosis
03/2010
1Acute Lung Injury
03/2010
1Osteosarcoma (Osteogenic Sarcoma)
02/2010
1Pulmonary Emphysema
12/2006
1Chorioamnionitis
12/2006
1Choriocarcinoma
11/2006
1Adenocarcinoma
07/2005

Drug/Important Bio-Agent (IBA)

12Laminin (Merosin)IBA
01/2020 - 01/2003
9Proteins (Proteins, Gene)FDA Link
12/2021 - 08/2006
8IntegrinsIBA
11/2019 - 03/2004
5Protein Isoforms (Isoforms)IBA
02/2010 - 12/2003
4laminin 8IBA
10/2005 - 10/2003
3laminin 10IBA
01/2018 - 01/2005
3Fibronectins (Fibronectin)IBA
01/2015 - 10/2004
2Therapeutic UsesIBA
01/2022 - 01/2020
2Messenger RNA (mRNA)IBA
11/2019 - 10/2005
2LigandsIBA
11/2019 - 05/2012
2AutoantigensIBA
01/2018 - 02/2009
2AutoantibodiesIBA
02/2015 - 02/2009
2nephronectinIBA
01/2013 - 05/2012
2Matrix Metalloproteinase 14 (MT1-MMP)IBA
11/2011 - 04/2005
2KalininIBA
03/2010 - 01/2005
2Transcription Factors (Transcription Factor)IBA
11/2006 - 12/2003
2laminin 1IBA
03/2006 - 03/2003
2Antisense OligonucleotidesIBA
10/2005 - 10/2003
2laminin 9IBA
01/2005 - 08/2004
1perlecanIBA
01/2022
1Epoprostenol (Prostacyclin)FDA LinkGeneric
11/2021
11,3,4,6- tetra- O- acetyl- 2- azido- 2- deoxyglucopyranose (TAAD)IBA
01/2021
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
01/2020
1RNA (Ribonucleic Acid)IBA
11/2019
1Proto-Oncogene Proteins c-sis (Platelet Derived Growth Factor B)IBA
11/2019
1atelocollagenIBA
01/2019
1Immunoglobulin G (IgG)IBA
01/2018
1alpha-SynucleinIBA
01/2018
1AntigensIBA
01/2018
1AntibodiesIBA
01/2018
1Laminin ReceptorsIBA
01/2017
1Pharmaceutical PreparationsIBA
01/2016
1Myosin Type IIIBA
05/2013
1CollagenIBA
05/2013
1Egtazic Acid (EGTA)IBA
05/2013
1Dynamins (Dynamin)IBA
05/2013
1TetraspaninsIBA
05/2013
1Concanavalin AIBA
01/2013
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2013
1Dexamethasone (Maxidex)FDA LinkGeneric
11/2011
1Fibrillin-1IBA
11/2011
1FurinIBA
04/2010
1Conditioned Culture MediaIBA
02/2010
1laminin gamma 1IBA
02/2009
1Glycoproteins (Glycoprotein)IBA
11/2008
1alpha-1,6-mannosylglycoprotein beta 1,6-N-acetylglucosaminyltransferaseIBA
11/2008
1factor AIBA
11/2008
1Annexin A2 (Annexin II)IBA
12/2006
1Immunoglobulin M (IgM)IBA
12/2006
1laminin AIBA
11/2006
1Peptide Hydrolases (Proteases)FDA Link
04/2005
1Metalloproteases (Metalloproteinases)IBA
04/2005

Therapy/Procedure

5Transplantation
01/2020 - 01/2003
4Therapeutics
01/2022 - 10/2003
1Tissue Transplantation
01/2020
1Ligation
01/2019